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Two men wake up at opposite sides of a dirty, disused bathroom, chained by their ankles to pipes. Between them lies a dead man loosely clutching a hand-held tape player and a handgun. Each finds a tape the perfect fit for the player in their back pocket. They play the tapes. One is threatened, the other isn’t. But they have a task: One must kill the other by 6:00, or his wife and daughter will die. They find hacksaws in a toilet, and try to cut the chains, but it doesn’t work. They are the two newest victims of the Jigsaw Killer. In a flashback, we learn of Amanda, a girl who falls victim to the Jigsaw Killer. On her head is a mask, which is hooked into her lower jaw. There is a timer on it. Only one key will unlock it, and that key is in the digestive tract of her cell mate who lies paralyzed on the opposite side of the room. If she doesn’t unlock the mask in time, her lower jaw will be ripped wide open. She survives, but her cell mate doesn’t. Through a series of flashbacks, we learn of more victims, and of the nearly-successful capture of the Jigsaw Killer, who doesn’t actually kill his victims. Instead, he finds ways to make them kill either themselves, or each other, and he thinks the entire ‘game’ out perfectly, with no other ways out. Or so it would seem.

Max has lived a mundane life as a cab driver for twelve years. The faces have come and gone from his rear-view mirror: people and places he’s long since forgotten—until tonight. Vincent is a contract killer. When an off-shore narco-trafficking cartel learns that they’re about to be indicted by a federal grand jury, they mount an operation to identify and kill the key witness, and the last stage is tonight. It is on this very night that Vincent has arrived—and five bodies are supposed to fall. Circumstances cause Vincent to hijack Max’ taxicab, and Max becomes collateral—an expendable person who’s in the wrong place at the wrong time. Through the night, Vincent forces Max to drive him to each assigned destination. And as the L.A.P.D. and F.B.I. race to intercept them, Max and Vincent’s survival become dependent on each other, in ways neither would have imagined.

Drugs. They consume mind, body and soul. Once you’re hooked, you’re hooked. Four lives. Four addicts. Four failures. Doing their best to succeed in the world, but failing miserably, four people get hooked on various drugs. Despite their aspirations of greatness, they succumb to their addictions. Watching the addicts spiral out of control, we bear witness to the dirtiest, ugliest portions of the underworld addicts reside in. It is shocking and eye-opening but demands to be seen by both addicts and non-addicts alike.

A young man (Evans) receives a call on his cellular phone from a woman (Basinger) who says she’s been kidnapped, and thinks she’s going to be killed soon, along with her husband and son who the kidnappers have gone after next. The catch? She doesn’t know where she is… and his cell phone battery might go dead soon.

Mort Rainey (Depp), a writer just coming off of a troublesome divorce with his ex-wife, Amy (Bello), finds himself stalked at his remote lake house by a psychotic stranger (Turturro) who claims Mort stole his best story idea (changing just the ending)… (Hutton plays Bello’s new boyfriend; Dutton plays a private investigator hired to make Turturro’s character leave Mort alone.)

Nicholas Van Orton is a very wealthy San Francisco banker, but he is an absolute loner, even spending his birthday alone. In the year of his 48th birthday (the age his father committed suicide) his brother Conrad, who has gone long ago and surrendered to addictions of all kinds, suddenly returns and gives Nicholas a card giving him entry to unusual entertainment provided by something called Consumer Recreation Services (CRS). Giving up to curiosity, Nicholas visits CRS and all kinds of weird and bad things start to happen to him.